Blood transfusion in critical care

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Blood transfusion in critical care

Blood transfusion is frequent in critical care. Transfusion raises the mass of transfused blood components and is lifesaving in acute hemorrhage. In massive transfusion (>10 units of red blood cells), early attempts to restore coagulation function appear helpful. Transfusion in non-bleeding patients is largely prophylactic, is seldom evidence-based, and may be deleterious. In hemodynamically st...

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Management of anaemia and blood transfusion in critical care - implementing national guidelines in ICU

Anaemia in intensive care is common, with approximately 50% of patients receiving a red cell transfusion. Recognised complications from transfusion include 'transfusion associated lung injury', infection, and organ failure progression. Most cohort studies show a positive relationship between red cell transfusion and adverse outcomes. In 2012, the British Committee for Standards in Haematology i...

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A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group.

BACKGROUND To determine whether a restrictive strategy of red-cell transfusion and a liberal strategy produced equivalent results in critically ill patients, we compared the rates of death from all causes at 30 days and the severity of organ dysfunction. METHODS We enrolled 838 critically ill patients with euvolemia after initial treatment who had hemoglobin concentrations of less than 9.0 g ...

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Clinical practice guideline: red blood cell transfusion in adult trauma and critical care.

OBJECTIVE To develop a clinical practice guideline for red blood cell transfusion in adult trauma and critical care. DESIGN Meetings, teleconferences and electronic-based communication to achieve grading of the published evidence, discussion and consensus among the entire committee members. METHODS This practice management guideline was developed by a joint taskforce of EAST (Eastern Associ...

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The implementation of a blood conservation strategy in critical care on transfusion requirements

Introduction Patients admitted to intensive care units (ICUs) are commonly affected by anaemia, which is contributed to by iatrogenic blood loss from diagnostic testing [1], with potential risks of increasing transfusion requirements and negative effect on outcomes [2]. Recently published guidelines make several recommendations for the management of anaemia and red blood cells (RBCs) transfusio...

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ژورنال

عنوان ژورنال: F1000 Medicine Reports

سال: 2009

ISSN: 1757-5931

DOI: 10.3410/m1-56